Can BOTOX® Lift Your Spirits?

Earlier this year, TIME magazine published a cover story exploring the many uses of BOTOX® injectable. Los Angeles-area women and men have certainly seen it used for years to smooth out frown lines and crow’s feet, and Dr. Derek Jones alone has performed more than 100,000 procedures. Its ability to treat everything from gummy smiles to hyperhidrosis to migraines is becoming increasingly well known. That said, the TIME article highlighted another use that is currently under investigation: improving the symptoms of people with depression.

Admitting that the “how” is still unclear, researchers working with BOTOX® manufacturer Allergan are currently exploring via clinical trials whether the injectable is suitable for treating depression. The leading theory is that a face free of frown lines simply looks happier, and that has an impact on mood. Whether a person “feels” different based on they look or feels more positivity thanks to people responding to pleasant facial expressions with positivity of their own remains to be determined.

What is known, however, is that a small study conducted in 2014 revealed that just more than half of 74 people suffering from major depressive disorder reported an improvement in their symptoms six weeks after receiving BOTOX®. The 52 percent was a marked difference from the 15 percent of study participants who reported similar improvements after receiving a placebo.

No matter the ultimate result of the clinical trial, the evidence is clear: BOTOX® is an effective tool for making people feel better—even if it’s just due to the knowledge that they look younger and less stressed. At Skin Care & Laser Physicians of Beverly Hills, Dr. Derek Jones, Dr. Naissan Wesley, and Dr. Jeanette Black use the muscle-relaxer for cosmetic reasons, and they can all report that they’ve seen patients leave happier than they arrived.

Learn more about BOTOX® from the Los Angeles area’s Skin Care & Laser Physicians of Beverly Hills. Call (310) 246-0495 or get info by visiting

Written by Dr. Derek Jones

Dr. Derek Jones is a renowned Los Angeles and Beverly Hills area dermatologist practicing in cosmetic and general dermatology.