What Are Off-Label Uses of Injectable Fillers?

Dermal fillers are soft synthetic or natural substances designed to add volume to the layers of skin as a replacement for collagen, hyaluronic acid, and other elements that make it supple and firm. Fillers counteract deep wrinkles, and some types lift or enlarge certain features to create a more pleasing, youthful appearance. In addition to their standard, on-label uses, there are also other benefits of JUVEDERM® and other injectable fillers that our Los Angeles-based Skin Care and Laser Physicians of Beverly Hills team knows many patients may not be aware.

While Dr. Derek Jones and other board-certified dermatologists at the practice have contributed greatly to numerous dermal filler FDA trials, the term “off-label” simply means that the treatment is being used in a way that it is not advertised for and has not been officially specified by the FDA. This may mean, for example, using a medication to treat a condition it is not approved for, administering it in a different way, or changing the dosage to better suit the patient.

These under-the-radar uses, also known as off-label indications, are common, legal, and generally safe when performed by a provider who knows what they’re doing.

Physicians have the discretion to use FDA-approved drugs for other uses if they determine, based on their expertise, that the medications would be suitable for a patient and have discussed the option with them.

For instance, Juvederm Volbella® XC gel is approved for lip augmentation and minimizing lip lines but is often also used on the delicate tear troughs area to correct hollowness and dark circles under the eyes. Providers sometimes use Juvederm Voluma® XC to fill out sunken-in temples.

RADIESSE® is a semi-permanent soft tissue filler made of calcium particles and FDA-approved for treating moderate to severe wrinkles and folds. It is also used by some doctors in a hyper-diluted form for cellulite or dimples on the butt and thighs, or irregularities on the abdomen. It is believed to provide structural support to some of these areas, firming them up in the process. Some other popular off-label uses for dermal fillers include adding volume to earlobes, liquid rhinoplasties, and treating knee and elbow wrinkles.

Have questions about the dermal fillers available for Los Angeles patients at Skin Care and Laser Physicians of Beverly Hills? We’ll help you find everything you need and ensure that your procedure goes as smoothly as possible. Let us know more about your goals: Call 310-246-0495 or message us about a consultation.

Written by Dr. Derek Jones

Dr. Derek Jones is a renowned Los Angeles and Beverly Hills area dermatologist practicing in cosmetic and general dermatology.